PUBBLICAZIONI

  1. Bazzo, R.; Esposito, G.; Pastore, A. Two Dimensional Techniques in Proton NMR of Proteins.  Chimica Oggi, 25, 1 – 9 (1986).
  2. Bazzo, R.; Boyd, J.; Campbell, I. D.; Soffe, N. Diagrammatic Representation of Both In-Phase and Anti-Phase Coherence Transfer Processes with a Simple Application. J. Magn. Reson., 73, 369 –  375 (1987).
  3. Bazzo, R.; Boyd, J. A Theoretical Analysis of Homonuclear Cross Polarization Coherence Transfer in Liquids. J. Magn. Reson., 75, 218 –  233 (1987).
  4. Bazzo, R.; Campbell, I. D. Pure Phase 2D Homonuclear Cross Polarization in Liquids. J. Magn. Reson., 76, 358 – 363 (1988).
  5. Bazzo, R.; Tappin, M.; Pastore, A.; Harvey, T. S.; Carver, J.; Campbell, I. D. The Structure of Melittin: a Proton NMR Study in Methanol.   Eur. J. of Biochem., 173, 139 – 146 (1988).
  6. Bazzo, R.; Boyd, J. Pulse Shaping and Selective Excitation: the Effect of Scalar Coupling.  J. Magn. Reson., 80, 568 – 576  (1988).
  7. Esposito, G.; Gibbons, W. A.; Bazzo, R.  Phase Coherence and Solvent Suppression   in Rotating Frame Correlation Experiments in Liquids.   J. Magn. Reson., 80,  523 –  530 (1988).
  8. Bazzo, R.; Edge, C. J.; Rademacher, T. W.; Dwek, R. A. Extracting Subspectra from Overlapping Regions: DOUBLE TOCSY.  J. Magn. Reson., 86, 199 –  208 (1990).
  9. Edge, C. J.; Singh, U. C.; Bazzo, R.; Taylor, G. L.; Dwek, R. A.; Rademacher,  T. W. 500 picoseconds molecular dynamics in water of the Mana 1-2  Man a  glycosidic linkage present in Asn-linked oligomannose type structures in glycoproteins.    Biochem., 29, 1971 – 1974 (1990).
  10. Wooten, W.; Bazzo, R.; Edge, C. J.; Dwek, R. A.; Rademacher, T.W. Uncertainties in structural determination of oligosaccharide conformation, using measurements of Nuclear Overhauser Effects. Res., 203, 13 – 17 (1990).
  11. Wooten, W.; Bazzo, R.; Edge, C. J.; Zamze, S.; Dwek, R. A.; Rademacher, T. W. The Primary Sequence Dependence of Rotamer Distribution in Oligomannose Oligosaccharides. Bioph. J., 18, 139 – 148 (1990).
  12. Bazzo, R.; Edge, C. J.; Wormald, M. R.; Rademacher, T. W.; Dwek, R. A. Complete computer simulation of ROESY experiments, including Hartmann-Hahn effects. Chem. Phys. Lett., 174, 313 – 317 (1990).
  13. Breeze, A. L.; Harvey, T. S.; Bazzo, R.; Campbell, I. D. Solution Structure of Human Calcitonin Gene- Related Peptide by Proton NMR and Distance Geometry with Restrained Molecular Dynamics. Biochemistry, 30, 575 – 582 (1991).
  14. Dempsey, C. E.; Bazzo, R.; Harvey, T. S.; Syperek, I.; Boheim, G.; Campbell, I. D. Contribution of proline – 14 to the structure and actions of melittin. FEBS Lett., 281, 240 – 244 (1991).
  15. Wormald, M. R.; Wooten, E. W.; Bazzo, R; Edge, C. J.; Feinstein, A.; T.W. Rademacher, T. W.; Dwek, R. A. The conformational effects of N-glycosilation on the tailpiece from serum IgM. Eur. J. Biochem., 198, 131 – 139 (1991).
  16. Cicero, D. O.; Iribarren, A.; Bazzo, R. Conformational Analysis by NMR Spectroscopy of 2′-Deoxy-2′-C-Alkyl-nucleosides: Building Blocks of New Antisense Fragments. Applied Mag. Reson., 7, 95 – 106 (1994).
  17. Cicero, D. O.; Barbato, G.; Bazzo, R. The NMR analysis of molecular flexibility in solution (NAMFIS): a new method for the study of complex distributions of rapidly exchanging  conformations.  Application to a 13 residue peptide with an 8 residue loop.  J. Am. Chem. Soc., 117, 1027 – 1033 (1995).
  18. Bazzo, R.; Cicero, D. O.; Barbato, G. A new HCACO 3D pulse sequence with optimized resolution and sensitivity. Application to the 21 kDa Protein Human Interleukin-6.    J. Magn. Reson., Series B,  107, 189 – 191 (1995).
  19. Cicero, D. O.; Barbato, G.; Bazzo, R. A new program for the conformational analysis by NMR of the sugar ring of nucleosides and nucleotides in solution: HETROT. Application to the sugar ring of AZT in solution.    Tetrahedron, 51, 10303 – 10308 (1995).
  20. Bianchi, E.; Folgori, A.; Wallace, A.; Nicotra, M.; Acali, S.; Phalipon, A.; Barbato, G.; Bazzo, R.; Cortese, R.; Felici, F.; Pessi, A. Selection of peptides with pre-determined structure from a conformationally homogeneous combinatorial peptide library. Trends in Peptide Research, 27, 251 – 260 (1995).
  21. Bazzo,R.; Barbato, G.; Cicero, D. O. Accurate measurement of heteronuclear long-range coupling constants from 1D-subspectra in crowded spectral regions. J. Magn. Reson., Series A, 117, 267 – 278 (1995). 
  22. Bianchi, E.; Folgori, A.; Wallace, A.; Nicotra, M.; Acali, S.; Phalipon, A.; Barbato, G.; Bazzo, R.; Cortese, R.; Felici, F.; Pessi, A. A Conformationally Homogeneus Combinatorial Peptide Library. J. Mol. Biol., 247, 154 – 160  (1995). 
  23. Bazzo, R.; Barbato, G.; Cicero, D. O. A new three-dimensional pulse sequence for correlating intraresidue NH, N, and CO chemical shifts in 13C, 15N labelled proteins. J. Magn. Reson, Series B, 110, 65 – 75 (1996). 
  24. G. Barbato, G.; Cicero, D. O.; Bianchi, E.; Pessi, A.; Bazzo, R. High resolution solution structure of two members of a conformationally homogeneous combinatorial peptide library based on the classical zinc finger motif. J. Biomolecular NMR, 8, 36 – 48 (1996). 
  25. Bianchi, E.; Barbato, G.; Wallace, A.; Cortese, R.; Felici, F.; Bazzo, R.; Pessi, A. The Zinc Finger Motif as a conformation – inducing template for selection – driven design of peptidomimetics. Solid Phase Synthesis and Combinatorial Chemical Libraries: Mayflower Scientific, Birmingham K., 159 – 164 (1996). 
  26. Carlomagno, T.; Mantile, G.; Bazzo, R.;   Paolillo, L.; Miele, L.; Mukherjee, A. B.;  Barbato, G. Resonance assignments and secondary structure determination and stability of the human uteroglobin (cc10kDa) protein with heteronuclear multidimensional NMR  J. Biomolecular NMR., 9, 35 – 46 (1997).
  27. Urbani, A.; Bazzo, R.; Nardi, M. C.; Cicero, D. O.; De Francesco, R.; Steinkühler, C.; Barbato, G. The Metal Binding Site of the Hepatitis C Virus NS3 Protease. A Spectroscopic Investigation. J. Biol. Chem., 273, 18760 – 18769 (1998).
  28. Bazzo, R.; Cicero, D. O.; Barbato, G. Selective Correlation of Amide Groups to Glycine Alpha Protons and of Arginine Guanidine Groups to Delta Protons in Proteins by Multiple Quantum Spectroscopy. J. Magn. Reson., 136, 15 – 21 (1999).
  29. Barbato, G.; Cicero, D. O.; Nardi, M. C.; Steinkühler, C.; Cortese, R.; De Francesco, R.; Bazzo, R. The solution structure of the N-terminal proteinase domain of the Hepatitis C Virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J. Mol. Biol., 289, 371-84 (1999).
  30. Cicero, D. O.; Barbato, G.; Koch, U.; Ingallinella, P.; Bianchi, E.; Nardi, M.C.; Steinkühler, C.; Cortese, R.; Matassa, V.; De Francesco, R.; Pessi, A.; Bazzo, R. Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the Human Hepatitis C Virus NS3 protein by NMR and Modelling Studies. J. Mol. Biol., 289, 385-96 (1999).
  31. Barbato, G.; Cicero, D. O.; Cordier, F.; Narjes, F.; Gerlach, B.; Sambucini, S.; Grzesiek, S.; Matassa, V. G.; De Francesco, R.; Bazzo, R.. Inhibitor binding induces active site stabilisation of the HCV NS3 protein serine protease domain. Embo J., 19, 1195-1206 (2000).
  32. Cicero, D. O.; Barbato, G.; Bazzo, R. Sensitivity Enhancement of a Two-Dimensional Experiment for the Measurement of Heteronuclear Long-Range Coupling Constants, by a New Scheme of Coherence Selection by Gradients. Magn. Reson., 148, 209-213 (2001).
  33. Bazzo, R.; Barbato, G.; Cicero, D. O. Improved Sensitivity in Indirect Monitoring of Chemical Shifts of Proton-Heteronuclear spin pairs (1H – 13C and 1H – 15N) in 3D and 4D NMR Spectroscopy. J. Biomol. NMR., 19, 261-266 (2001).
  34. Cicero, D. O.; Barbato, G.; Koch, U.; Ingallinella, P.; Bianchi, E.; Sambucini, S.; Neddermann, P.; De Francesco, R.; Pessi, A.; Bazzo, R. Measurement of homonuclear three-bond J(HN-HA) coupling constants in unlabeled peptides complexed with labeled proteins. Application to a decapeptide inhibitor bound to the proteinase domain of the NS3 protein of Hepatitis C Virus (HCV).  Biomol. NMR, 20, 23-29 (2001).
  35. Ingallinella, P.; Fattori, D.; Altamura, S.; Steinkuhler, C.; Koch, U.; Cicero, D. O.; Bazzo, R.; Cortese, R.; Bianchi, E.; Pessi, A. Prime site-binding Inhibitors of a Serine Protease: NS3/4A of Hepatitis C Virus. Biochemistry, 41, (17) 5483 – 5492 (2002).
  36. Barbato, G.; Bianchi, E.; Ingallinella, P.; Hurni, W. H.; Miller, M. D.; Ciliberto, G.; Cortese, R.; Bazzo, R.; Shiver. ; Pessi, A. Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion. J. Mol. Biol., 330, (5) 1101 – 1115 (2003).
  37. Espeseth, A. S.; Xu, M.; Huang, Q.; Coburn, C. A.; Jones, K. L. G.; Ferrer, M.; Zuck, P. D.; Strulovici, B.; Price, E. A.; Wu, G.; Wolfe, A. L.; Lineberger, J. E.; Sardana, M.; Tugusheva, K.; Pietrak, B. L.; Crouthamel, M. C.; Lai, T.; Dodson, E. C.; Bazzo, R.; Shi, X. P.;  Simon, A. J.;  Li, Y.;  J. Hazuda, D. J. Compounds that bindAPP and inhibit AB Processing in vitro suggest a novel approach to Alzheimer disease therapeutics. J. Biol. Chem., 280, (18) 17792 – 17797 (2005).
  38. Cicero, O. D.; Contessa, G. M.; Paci, M.; Bazzo, R. HACACO revisited: Residual dipolar coupling measurements and resonance assignments in proteins. Magn. Reson., 180, 222-228 (2006).
  39. Eliseo, T:; Gallo, M., Melis; Paci, M.; Bazzo, R.; Cicero, D. O. Single scan TROSY and E:COSY suite of experiments for the measurement of residual dipolar couplings in proteins. Spectroscopy: An Int. J., 20, 153-167 (2006)
  40. Bottomley, M. G., Muraglia E., Bazzo, R; Carfì A: Molecular insights into quorum sensing in the human pathogen Pseudomonas aeruginosa from the structure of the virulence regulator LasR bound to its autoinducer. Bio.l Chem., 282 (18), 13592 – 600 (2007)